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Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show is a window into the latest innovations in digital health and the changing dynamic between doctors and patients.

Topics on the show include

  • the emergence of personalized medicine and breakthroughs in genomics
  • advances in biopharmaceuticals
  • age related diseases and aging in place
  • using big data from wearables and sensors
  • transparency in the medical marketplace
  • challenges for connected health entrepreneurs

The audience includes researchers, medical professionals, patient advocates, entrepreneurs, patients, caregivers, solution providers, students, journalists, and investors.

Dec 27, 2021

Dr. Betty Raman is the Senior Clinical Research Fellow in the Radcliffe Department of Medicine at the University of Oxford and has been studying the effects of COVID-19 since the pandemic began to better understand the effects of COVID on multiple organ systems.

Betty elaborates, "At Oxford, we've led a program where hundreds of patients recovering from COVID-19 volunteered to participate in our study. We undertook comprehensive assessments on magnetic resonance imaging, as well as cardiopulmonary exercise testing and blood tests."

"What has come out from all this work is that a significant proportion of people recovering from moderate to severe and even mild COVID continue to experience lingering symptoms of fatigue, pain in various parts of the body, breathlessness and difficulty breathing. Some patients also report post-exertional breathlessness, post-exertional malaise."

"So, we were quite interested in this new drug that Axcella wanted to test out, which had potential benefits for mitochondrial dysfunction, which we think may be playing a role in some symptoms that long COVID patients have experienced. And so, we have designed a study, which is aimed at fatigue dominant long COVID patients who are recovering from COVID-19 and continue to experience symptoms of fatigue. And we're going to see whether this new treatment has any effects on symptoms of fatigue in patients."

@BR_CMR #LongCovid #ChronicFatigueLongCovid #OxfordLongCovid #AxcellaLongCovid #LongHaulers #COVID19 #COVID #ClinicalTrials

Rdm.ox.ac.uk

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Dr. Betty Raman