Welcome to the Empowered Patient Podcast with Karen Jagoda. This show is a window into the latest innovations in applying generative AI, novel therapeutics and vaccines, and the changing dynamics in the medical and healthcare environment. One focus is on how providers, pharmaceutical companies, and payers are empowering patients. In addition, conversations are often about how providers, care facilities, pharmaceutical companies, and payers are being empowered by technology to improve patient outcomes and reduce friction across the healthcare landscape.
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Focus on Protein Misfolding Leading to Drug Discovery Through Use of Supercomputer and Computational Chemistry with Manolo Bellotto Gain Therapeutics TRANSCRIPT
Download PDFMay 24, 2021
Manolo Bellotto, PhD is General Manager and President Gain Therapeutics and dedicated to redefining drug discovery through the use of supercomputers and proprietary algorithms to understand rare diseases and diseases where there is a high medical need related to protein misfolding. These indications include cancer, neurodegenerative, metabolic and inflammatory diseases.
While traditional drug discovery around protein misfolding was through high-throughput screening, Gain can efficiently identify a select group of molecules that can potentially correct misfolding or induce misfolding of specific proteins. In a short period of time, using a personalized approach in each different target, they have the biological characterization to see if they can intervene on the protein, potentially leading to a pharmacological solution.
@GainThera #ProteinMisfolding #DrugDiscovery #RareDisease #Oncology #LysosomalStorageDisorders #Neurodegenerative #Supercomputer #technology #ComputationalChemistry
