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Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show offers a glimpse into the latest innovations in applying generative AI, novel therapeutics and vaccines, and the evolving dynamics in the medical and healthcare landscape. One focus is on how providers, pharmaceutical companies, and payers are empowering patients.  In addition, conversations often focus on how technology is empowering providers, care facilities, pharmaceutical companies, and payers to improve patient outcomes and reduce friction across the healthcare landscape.  Popular Topics Include: Virtual and digital health Use of AI, ML, and robots for clinical and administrative purposes  Value-based healthcare  Precision and stratified medicine Next-generation immuno, cell, and gene therapies Vaccines for infectious diseases and oncology Biomarkers and diagnostics Rare diseases MedTech and medical devices Clinical trials  Population health Chronic conditions l Clinician and staff burnout Smart hospitals The audience includes life science leaders, researchers, medical professionals, patient advocates, digital health entrepreneurs, patients, caregivers, healthcare solution providers, students, journalists, and investors.

Mar 12, 2024

Fengru Lin, Co-Founder and CEO of TurtleTree, is applying precision fermentation technology to produce high-value ingredients for food and beverages without the need for animals. This biotech company's first goal is to expand the production of lactoferrin, a protein found in small quantities in milk that has been shown to promote gut health and immunity. Finding a scalable way to produce lactoferrin will lead to adding this iron-binding element to plant-based milks and energy drinks.  

Fengru explains, "A couple of years ago, I was learning how to make cheese as a hobby. It was quite a fanatic period of time. I went up to Vermont from Singapore for a couple of weeks to learn how to make cheese and I wanted to replicate this whole process back in Singapore. But in Singapore, we have no access to cows, we have no access to raw, fresh milk. So, I had to go down to Indonesia and Thailand to look for milk. In this journey, I was exposed to a lot of challenges around the dairy industry, things like contract farming, things like antibiotics, and hormones being pumped into the cows. As a result, the milk quality always suffers, the mozzarella couldn't stretch, it's not enough calcium, not enough nutrients in the milk. So, I gave up that whole idea and was still working for Google."  

"So, we bootstrapped initially, brought in some scientists, did a lot of research, and filed our first patent. The technology requires getting memory cells and culturing the cells to express full-function milk, all 2,000 different ingredients in milk. We had our early success and quickly brought this technology to some of the biggest dairy companies in the world, folks like Fonterra and Abbott, and told them, "Hey, we can make milk. What do you think?"

"Very quickly they came back with feedback saying, "Well, great that you can make milk, but milk is $2 a gallon. I don't think you can get to the price point anytime soon. You should really be focused on high-value ingredients that are found in milk." So they gave us a list of half a dozen proteins and ingredients that we should look at, and at the top of the list is lactoferrin because of all these great benefits and the high price point it is today. You guys should be focused on the high-value ingredients that are low in supply across the market so you can address this accessibility problem and not try to reproduce a commodity like milk. So that's how we started and where we are today. We just got our FDA Self GRAS status in November last year, so we've started to commercialize this lactoferrin."

#TurtleTree #FunctionalFood #Lactoferrin #Protein #PrecisionFermentation #Milk #SustainableFoodProduction #Nutrition

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