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Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show is a window into the latest innovations in applying generative AI, novel therapeutics and vaccines, and the changing dynamics in the medical and healthcare environment. One focus is on how providers, pharmaceutical companies, and payers are empowering patients.  In addition, conversations are often about how providers, care facilities, pharmaceutical companies, and payers are being empowered by technology to improve patient outcomes and reduce friction across the healthcare landscape.

Popular Topics

  • Virtual and digital health
  • Use of AI, ML, and LLM in healthcare and drug discovery, development, trials
  • Value-based healthcare 
  • Precision and stratified medicine
  • Integration of digital technology into existing workflow and procedures 
  • Next-generation immuno, cell, and gene therapies
  • Vaccines
  • Biomarkers, sequencing, and imaging
  • Rare diseases
  • MedTech and medical devices
  • Clinical trials
  • Addressing Social Determinants of Health
  • Treating chronic conditions like obesity and pain
  • Clinician and staff burnout

The audience includes life science leaders, researchers, medical professionals, patient advocates, digital health entrepreneurs, patients, caregivers, healthcare solution providers, students, journalists, and investors. 

 

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Empowered Patient Solutions

Jul 24, 2023

Jeff Hackman, CEO of Comera Life Sciences, recognizes the need to find a more efficient, patient-friendly solution for receiving biologics rather than being administered by IV therapy. Using the SQore platform, a proprietary technology, Comera is reformulating IV biologics to Sub-Q utilizing small molecule chemistry and an understanding of excipients. Seven out of ten global medicines are biologics, and most are administered by IV, providing a tremendous opportunity to expand access to biologics using Sub-Q technology.

Jeff elaborates, "Our mission is to transform these biologic therapies into a different form, a subcutaneous form. That form takes on the ability of these patients to administer these medicines for themselves, at home, at school, and at work. So really, what the summary of this mission is, through the freedom of self-injectable care, we hope that these patients can live a life without the burden of this therapy and the ability to be able to make their lives more livable."

"Excipients have been around for decades. They often fail to reduce the viscosity necessary to get these high-potency biologics into these small spaces, these small syringes, as you said. Our technology, which is called the SQore platform, allows this to happen more often, and it's such a significant impact that we have had multiple partnerships and collaborations with large pharma over the years to work with them to be able to do this."

"The issue you have around the science and the platform is that by taking and putting large molecules like this and these biologics into small spaces that are very potent, these biologics and antibodies stick together. So what our technology does is it's viscosity-reducing. That viscosity, you can think about it as when you put these biologics into a small syringe, they almost look like oil or glue."

"The ability to be able to stabilize these and to be able to get them to flow around each other and to be injected at these high potency levels is what our SQore platform does."

#ComeraLifeSciences #Biologics #IVInfusion #Subcutaneous #SubQ #Immunotherapy #SQore #Excipients

Comeralifesciences.com

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Comera