Preview Mode Links will not work in preview mode


Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show is a window into the latest innovations in applying generative AI, novel therapeutics and vaccines, and the changing dynamics in the medical and healthcare environment. One focus is on how providers, pharmaceutical companies, and payers are empowering patients.  In addition, conversations are often about how providers, care facilities, pharmaceutical companies, and payers are being empowered by technology to improve patient outcomes and reduce friction across the healthcare landscape.

Popular Topics

  • Virtual and digital health
  • Use of AI, ML, and LLM in healthcare and drug discovery, development, trials
  • Value-based healthcare 
  • Precision and stratified medicine
  • Integration of digital technology into existing workflow and procedures 
  • Next-generation immuno, cell, and gene therapies
  • Vaccines
  • Biomarkers, sequencing, and imaging
  • Rare diseases
  • MedTech and medical devices
  • Clinical trials
  • Addressing Social Determinants of Health
  • Treating chronic conditions like obesity and pain
  • Clinician and staff burnout

The audience includes life science leaders, researchers, medical professionals, patient advocates, digital health entrepreneurs, patients, caregivers, healthcare solution providers, students, journalists, and investors. 


Check out our new EmpoweredPatient.Solutions site where you can quickly search all of the Empowered Patient Podcast interviews by any word or phrase to identify useful resources, potential partners, and insights about the life sciences landscape.

Empowered Patient Solutions

Jul 8, 2024

Ed Esquenazi, Founder and CEO of Sirenas, is exploring the chemistry of marine organisms to accelerate drug discovery. Marine-based scientific elements are still poorly understood but have the potential to produce unique and useful compounds for drug development. There are stark differences between land-based organisms and marine-based organisms, which have evolved for much longer and, therefore, offer more diverse and complex chemistry. Using AI and machine learning, Sirenas has identified cancer-killing agents, anti-infective agents, and anti-inflammatory compounds from marine organisms and is developing marine-based personal care products. 

Ed explains, "We go out into the ocean, collect samples, we bring them back. We understand the different chemistry being produced in these organisms, identify and catalog it very carefully using instrumentation, and then figure out how that chemistry might impact biological systems, all with the goal of accelerating drug discovery. So the goal is to make the chemistry from marine organisms accessible to drug discovery."

"We discovered one of the most powerful antimalarials working with the Gates Foundation. We’ve also identified quite a few anti-inflammatory compounds. These are things that modulate the immune system in ways to dampen inflammation or, in some cases, actually accelerate inflammation. So, we’ve identified some of those with very interesting therapeutic paths."

"I think it’s a matter of diversity. A lot of the elements used in drug discovery traditionally have been based either on plants or bacteria, but land-based or synthetic, and they limit the diversity of the chemistry used in drug discovery. So, if you go into the ocean, you’re opening up a realm of very different components that can help accelerate the discovery of novel therapeutics."

#SirenasMD #MarineBasedDrugs #MarineOrganisms #DrugDiscovery #Algae

Download the transcript here