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Welcome to the Empowered Patient Podcast with Karen Jagoda.  This show is a window into the latest innovations in digital health and the changing dynamic between doctors and patients.

Topics on the show include

  • the emergence of precision medicine and breakthroughs in genomics
  • advances in biopharmaceuticals
  • age-related diseases and aging in place
  • using big data from wearables and sensors
  • transparency in the medical marketplace
  • challenges for connected health entrepreneurs

The audience includes researchers, medical professionals, patient advocates, entrepreneurs, patients, caregivers, solution providers, students, journalists, and investors.

Nov 16, 2023

Melinda Thomas, the COO and Co-Founder of Octave Bioscience is focused on delivering a new standard of care for multiple sclerosis and other neurodegenerative diseases.  The company aims to address the unmet needs of people living with MS using blood-based biomarkers, expanded imaging, and a clinical insights program. The solution includes an app, wearable sensors, and a nurse care partner to help patients and neurologists make better-informed treatment decisions.  

Melinda elaborates, "What we learned when we did about 150 interviews before we even started developing anything was, in MS specifically, there was no way to see what was going on beneath the surface. You didn't have a blood test that told you what was going on in the biology. So, we developed a blood test, 18 biomarkers analytically validated, that reveal underlying activated pathways and mechanisms that allow for accurate measurement of what's going on with their disease activity."  

"The tool used today is an MRI, which shows new or worsening lesions. It shows damage has occurred. So, the biomarker helps understand whether there is more disease activity that will eventually lead to these kinds of lesions. But also, if that is the gold standard, to understand if there are new or worsening lesions. We worked very hard with clinicians saying, "Where's the gap for you right now? What's the unmet need?" 

#OctaveBioscience #MS #MultipleSclerosis #NeurodegenerativeDiseases #Biomarkers #BloodTests

octavebio.com

Download the transcript here

Octave Bioscience